DERIVATIVES OF 1-(1-ADAMANTYL)ETHYLAMINE-N-ACYLAMINOACIDES AND THEIR ANTI-INFLUENZA ACTIVITY Russian patent published in 2015 - IPC C07C317/50 C07D209/20 A61P31/16 

Abstract RU 2572102 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel amino acid derivatives of 1-(1-adamantyl)ethylamine of general formula given below, and namely to compounds 1-3 in which , (compound 1); R1 = H, (compound 2) and , (compound 3). Claimed compounds have selective antiviral activity with respect to influenza A viruses, acts on strains, resistant to action of rimantadine hydrochloride, and can be applied in pharmacology and virology.

EFFECT: compounds 1 and 3 also have virucidal activity with respect to viruses of A type.

3 cl, 5 dwg, 5 ex

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RU 2 572 102 C1

Authors

Shibnev Vladimir Aleksandrovich

Derjabin Petr Grigor'Evich

Burtseva Elena Ivanovna

Garaev Timur Mansurovich

Finogenova Marina Pavlovna

Kirillova Elena Sergeevna

Botikov Andrej Gennadievich

Dates

2015-12-27Published

2014-12-26Filed