METHOD FOR OXIDIZED DEXTRAN OBTAINING Russian patent published in 2017 - IPC C08B37/02 

FIELD: pharmacology.

SUBSTANCE: method involves hydrogen peroxide addition to dextran aqueous solution to a final concentration of 0.25 to 5.0% in the solution, depending on the desired depth of dextran oxidation. The mixture is stirred, poured into a container with a flat inert surface and distributed in a thin layer. Simultaneous oxidation of dextran and drying of the desired product is performed at 90-95°C for 1-2 hours. Preferably, a 10% aqueous dextran solution with a molecular weight of 40 kDa or 70 kDa is used. Pallets made of glass, aluminium alloys, stainless steel, with ceramic or Teflon coating are used as an inert surface. Preferably, mixture layer thickness before oxidation and desired product drying is 1-3 mm.

EFFECT: improved method.

4 cl, 2 tbl, 3 ex