FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, experimental and clinical pharmacology. The substance of the method: oxidised dextran is dissolved in a tris-acetate buffer solution with pH 5.0-5.5; the prepared solution is added with biotin hydrazide in a relation to oxidised dextran equal to 1:(20-25); the prepared solution is heated to 80-90°C and settled for 30-60 minutes.
EFFECT: preparing the high-quality biotinylated derivative of oxidised dextran providing higher sensitivity of its immune immunoassay in blood serum.
3 cl, 2 dwg, 4 tbl, 4 ex
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