FIELD: chemistry.
SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.
EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.
8 cl, 10 tbl, 3 dwg, 31 ex
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Authors
Dates
2017-05-22—Published
2013-06-17—Filed