NEW INDANSULFAMIDNOE DERIVATIVES Russian patent published in 2017 - IPC C07C307/08 A61K31/18 A61K31/277 A61P25/08 

Abstract RU 2619937 C2

FIELD: chemistry.

SUBSTANCE: new indansulfamidnye derivatives or their pharmaceutically acceptable salt , such as N-[(1S)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfonamide, N-[(1S)-2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl]sulfamide, (+)-N-(2,2,4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl)sulfamide, are characterized by the effect of improving seizure severity index (score) in a murine model of kindling.

EFFECT: compound or salt thereof are assumed as a medicament for the treatment of epilepsy.

8 cl, 10 tbl, 3 dwg, 31 ex

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RU 2 619 937 C2

Authors

Kadzuta Yudzi

Vatanabe Toru

Sorimati Keiiti

Saito Minako

Kita Joiti

Tanaka Tosiaki

Khigasiyama Khiroyuki

Khanada Takakhisa

Teramoto Tetsuyuki

Kosasa Takasi

Isikava Yukio

Dates

2017-05-22Published

2013-06-17Filed