BIOLOGICALLY ACTIVE MOUTHWASH COMPOSITIONS WITH ESSENTIAL OILS WITHOUT ALCOHOL Russian patent published in 2017 - IPC A61K8/06 A61K8/34 A61K8/46 A61K8/92 A61K8/97 A61Q11/00 

FIELD: pharmacy.

SUBSTANCE: antimicrobial mouthwash compositions, comprising: an oil phase comprising one or more antimicrobial essential oils; solvent system; at least one alkyl sulfate surfactant; and an aqueous phase comprising water; wherein the mouthwash composition is a microemulsion comprising micelles with sizes less than approx. 200 nm, and the composition does not contain compounds affect the bioavailability. One composition version does not contain monohydric alcohols C₂-C₄ or contains up to 10% by monohydric alcohols C₂-C₄ volume of the total composition volume, wherein the solvent system comprises from 4% wt./vol. to 10 wt./vol. of propylene glycol and from 6 wt./vol. to 14 wt./vol. of sorbitol. The total amount of the solvent system is less than 20% wt./vol. Another composition version does not contain monohydric alcohols C₂-C₄. The amount of oil phase is 0.36 wt %; at least one alkyl sulfate surfactant - 0.35 wt %; the solvent system comprises 5 wt % to 13 wt % of propylene glycol and 10 wt % to 25 wt % of sorbitol at addition as 70% sorbitol solution.

EFFECT: above stated versions of mouthwash composition without alcohol or with low alcohol content possess high biocidal activity, are effective for halitosis prevention and removal, as well as for reduction of the number of microorganisms in the oral cavity, causing the formation of dental plaque and caries.

13 cl, 9 tbl, 8 ex