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2 621 862

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IPC

C07K7/08(2006-01-01)

C07K4/04(2006-01-01)

A61K31/95(2006-01-01)

A61K31/12(2006-01-01)

A61K31/538(2006-01-01)

(21) (22)

Application

2016127595, 2016-07-08

(24)

Start date

2016-07-08

(22)

Actual filing date

2016-07-08

(45)

Published

2017-06-07

(72)

Inventor

Bajtin Dmitrij MikhajlovichBakhlanova Irina VitalevnaPetukhov Mikhail GennadievichPobegalov Georgij EvgenevichKhodorkovskij Mikhail AlekseevichYakimov Aleksandr Pavlovich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Politekhnicheskij Universitet Petra Velikogo" Vo

FAMILY OF PEPTIDES - INHIBITORS OF RECA PROTEIN ACTIVITY, BLOCKING SOS-RESPONSE OF BACTERIA Russian patent published in 2017 - IPC C07K7/08 C07K4/04 A61K31/95 A61K31/12 A61K31/538

Abstract RU 2621862 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to novel peptide structures having antibacterial properties and can be used in medicine. A family of peptides having inhibitory activity against bacterial RecA proteins is claimed, as well as having the property of blocking the SOS-response of bacteria.

EFFECT: unlike the known analogs, the proposed peptides have greater conformational stability and are able to inhibit the activity of RecA protein with a sufficiently lowIC₅₀.

4 ex, 1 tbl, 5 dwg

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RU 2 621 862 C1

Authors

Bajtin Dmitrij Mikhajlovich

Bakhlanova Irina Vitalevna

Petukhov Mikhail Gennadievich

Pobegalov Georgij Evgenevich

Khodorkovskij Mikhail Alekseevich

Yakimov Aleksandr Pavlovich

Dates

2017-06-07—Published

2016-07-08—Filed