FIELD: pharmacology.
SUBSTANCE: method of invention comprises intra-articular introduction of agent containing pharmaceutically acceptable nafamostat salt, (2-hydroxypropyl)-β-cyclodextrin and chondroitin sulphate. The agent of the invention comprises nafamostat dimesylate, cyclodextrin enhancing solubility of nafamostat, as well as chondroprotective component - chondroitin sulphate.
EFFECT: use of the invention enables to achieve complete elimination of pathogen from the infected joint while reducing the total dose of nafamostat and injection frequency.
11 cl, 6 tbl, 3 dwg, 8 ex
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