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2 495 036

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IPC

C07D417/06(2006-01-01)

C07D417/14(2006-01-01)

A61K31/433(2006-01-01)

A61K31/4436(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2012118497/04, 2012-05-05

(24)

Start date

2012-05-05

(22)

Actual filing date

2012-05-05

(45)

Published

2013-10-10

(72)

Inventor

Gintsburg Aleksandr LeonidovichZigangirova Nailja AkhatovnaZajakin Egor SergeevichLujksaar Sergej IgorevichKapotina Lidija Nikolaevna

(73)

Holder

Federal'Noe Gosudarstvennoe Bjudzhetnoe Uchrezhdenie Institut Ehpidemiologii I Mikrobiologii Imeni Pochetnogo Akademika N.F. Gamalei" Ministerstva Zdravookhranenija I Sotsial'Nogo Razvitija Rossijskoj Federatsii

BIOLOGICALLY ACTIVE SUBSTANCES SUPPRESSING PATHOGENIC BACTERIA, AND METHOD FOR INHIBITING TYPE III SECRETION IN PATHOGENIC BACTERIA Russian patent published in 2013 - IPC C07D417/06 C07D417/14 A61K31/433 A61K31/4436 A61P31/04

Abstract RU 2495036 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to indolyl-substituted derivatives of thiadiazinones prepared from oxamic acid thiohydrazide of general formula: , wherein R represents H; R¹ represents pyridinyl; phenyl substituted by alkyl C1-C5, Hal, CF₃; R² represents H; alkyl C1-C5; -CH₂COOR⁴; benzyl substituted by Hal, OR⁴; benzoyl substituted by Hal, OR⁴, while R⁴ represents unsubstituted alkyl C1-C4.

EFFECT: there are prepared new compound which can find application in medicine for developing the therapeutic agent possessing pathogenic bacteria inhibitory activity.

2 cl, 2 dwg, 2 tbl, 13 ex

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RU 2 495 036 C1

Authors

Gintsburg Aleksandr Leonidovich

Zigangirova Nailja Akhatovna

Zajakin Egor Sergeevich

Lujksaar Sergej Igorevich

Kapotina Lidija Nikolaevna

Dates

2013-10-10—Published

2012-05-05—Filed