METHOD FOR PREDICTION OF POSTINFECTIOUS GASTROENTEROLOGICAL PATHOLOGY DEVELOPMENT IN CHILDREN, CONVALESCENTS Russian patent published in 2017 - IPC G01N33/50 A61B5/00 

FIELD: medicine.

SUBSTANCE: level of aspartate aminotransferase is determined in the blood serum in the acute period of the disease, linear discriminant functions of LDF₁ (absence of development of gastroenterological pathology) and LDF₂ (presence of development of gastroenterological pathology) are calculated according to formulas LDF₁ = -6.03+2.40X₁+0.83X₂+0.64X₃-1.42X₄+0.64X₅; LDF₂ = -12.63+2.75X₁+1.13X₂+0.93X₃+2.02X₄+5.09X₅, where X₁ is the nature of fever in the first day of the disease (1 - subfebrile: 37.0-37.9°C; 2 - febrile: 38.0-38.9°C; 3 - high febrile: 39.0-39.9°C; 4 - hyperpyretic: 40.0°C and more); X₂ is the frequency of liquid stool on the first day of the disease; X₃ is the number of episodes of vomiting on the first day of the disease; X₄ is the level of aspartate aminotransferase in serum in the acute period of the disease (0 - normal, 1 - elevated); X₅ is the use of antibacterial drugs for prehospital treatment (0 - no, 1 - yes). LDF₁ and LDF₂ values are compared, and the development of post-infection functional gastroenterological pathology is predicted if LDF₂>LDF₁.

EFFECT: method application will increase the efficiency of prevention and prevent formation of post-infectious diseases of the digestive organs of a functional nature, reduce the number of adverse outcomes of rehabilitation.

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