FIELD: pharmacology.
SUBSTANCE: method involves polymer dissolving in an organic solvent, film pouring on the surface, drug introduction, drying, at that, levomicetin is used as the drug, a pre-activated silk fibroin is used as the polymer. The invention can be used in medicine, for example, to cover external skin injuries.
EFFECT: method allows to obtain biodegradable and biocompatible films with a drug using a non-hazardous and non-volatile solvent while maintaining uniform drug distribution in the film creating an amorphous crystal structure that provides a given yield of the drug and preserves the original properties of the film.
3 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF MANUFACTURING POROUS MATERIAL FROM FIBROIN/CHITOSAN MIXTURE | 2004 |
|
RU2270209C1 |
| METHOD OF PRODUCING SILK FIBROIN BASED FILM FOR MAKING CONTACT LENSES | 2010 |
|
RU2443805C1 |
| CHITOSAN-BASED WOUND COVERING (VERSIONS) | 2015 |
|
RU2613112C2 |
| PROCESS OF MANUFACTURING MATERIAL FROM CELLULOSE-FIBRON MIX | 2007 |
|
RU2323282C1 |
| NATURAL SILK SOLVING METHOD | 2002 |
|
RU2217530C1 |
| SOLUTION FOR PREPARING CHITOSAN MATERIAL, METHOD FOR PREPARING HAEMOSTATIC MATERIAL OF THIS SOLUTION (VERSIONS) AND MEDICAL DEVICE WITH USING CHITOSAN FIBRES | 2011 |
|
RU2487701C2 |
| METHOD FOR OBTAINING HYDROGEL OF POLYVINYL ALCOHOL | 2016 |
|
RU2659164C1 |
| METHOD OF PRODUCING CHITOSAN IODO-DERIVATIVES | 2014 |
|
RU2575784C1 |
| BIOPOLYMERIC FIBRE, COMPOSITION OF FORMING SOLUTION FOR ITS OBTAINING, METHOD OF FORMING SOLUTION PREPARATION, LINEN OF BIOMEDICAL PURPOSE, BIOLOGICAL BANDAGE AND METHOD OF WOUND TREATMENT | 2010 |
|
RU2468129C2 |
| METHOD OF FORMATION OF THREE-DIMENSIONAL BIORESORBABLE STRUCTURES | 2017 |
|
RU2691752C1 |
