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(19)

(11)

2 625 796

(13)

(51)

IPC

C07D498/08(2006-01-01)

C07D515/08(2006-01-01)

A61K31/395(2006-01-01)

A61K31/407(2006-01-01)

A61K31/4353(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2014132046, 2013-01-08

(24)

Start date

2013-01-08

(22)

Actual filing date

2013-01-08

(45)

Published

2017-07-19

(72)

Inventor

Anzelm LilliBenner DevidBlank Zhan-BaptistGofreto DelfinKhaap VolfgangKhartmann GvidoKun BerndLyubbers TomasPeters Jens-UveShpinnler Beat

(73)

Holder

F. Hoffmann-La Roche Ag

MACROCYCLIC AMIDES AS PROTEASE INHIBITORS Russian patent published in 2017 - IPC C07D498/08 C07D515/08 A61K31/395 A61K31/407 A61K31/4353 A61P3/10

Abstract RU 2625796 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to a compound of formula

and to pharmaceutical compositions based on it and to the application in the treatment or prevention of diabetes, diabetic retinopathy, diabetic neuropathy, atherosclerosis, abdominal aortic aneurysm, chronic kidney diseases and tumours.

EFFECT: compound of the formula can be used as a drug.

17 cl, 1 tbl, 52 ex

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RU 2 625 796 C2

Authors

Anzelm Lilli

Benner Devid

Blank Zhan-Baptist

Gofreto Delfin

Khaap Volfgang

Khartmann Gvido

Kun Bernd

Lyubbers Tomas

Peters Jens-Uve

Shpinnler Beat

Dates

2017-07-19—Published

2013-01-08—Filed