METHOD OF DIFFERENTIAL DIAGNOSTICS OF TUMOURS OF ANOGENITAL MAMMARROW GLAND Russian patent published in 2017 - IPC A61B10/02 G01N33/53 

FIELD: medicine.

SUBSTANCE: for differential diagnosis of tumours of anogenital mammar-like glands, the tumour belongs to the group of tumours AMLG, localization of the tumour in the skin and its location in the skin. When it is located in the dermis or in the epidermis or if there is a connection between the tumour of the dermis and the epidermis, its good quality or malignancy is determined. After this, the histological pattern and architectonics of the tumour and their similarity to breast tumours are determined. When the tumour is located in the epidermis, its malignancy and in the presence of the pagetoid histological pattern of the tumour and its architecture similar to that of Paget's mammary disease, the presence or absence of malignant tumours of other organs that propagate to the epidermis and in the absence of expression of Uroplakin-III, PSA, S100, P63, as well as the absence of malignant tumours of other organs that spread to the epidermis, the primary extramammary disease of Paget is diagnosed. When the tumour is located in the dermis or if there is a connection between the dermal tumour and the epidermis, its good quality, histological pattern and architectonics, similar to the histological pattern and architectonics of Andra ductal papilloma of the breast, Papillary hydradenoma. The location of the tumour in the dermis, it's good quality, histological pattern and architectonics, similar to the histological pattern and architectonics of the fibroadenoma of the breast, is diagnosed Fibroadenoma of the mammar-like glands (MLG). The location of the tumour in the dermis, it's good quality, histological pattern and architectonics, similar to the histological pattern and architectonics of the adenoid tumour of the breast, an Adenosic tumour of the MLG is diagnosed. With the location of the tumour in the dermis, it's good quality, histological pattern and architectonics, similar to the histological pattern and architectonics of the lactating adenoma of the breast, are diagnosed Lactating adenoma of the MLG. With the location of the tumour in the dermis, it's good quality, histological pattern and architectonics, similar to the histological pattern and architectonics of a benign breast cancer tumour, the Benign filoid tumour of the MLG is diagnosed. With the location of the tumour in the dermis, its malignancy, histological pattern and architectonics, similar to the histological pattern and architectonics of the malignant filoid breast tumour, the Malignant filoid tumour of the MLG is diagnosed. With the location of the tumour in the dermis, its malignancy, histological pattern and architectonics, similar to the histological pattern and architectonics of the ducal carcinoma in situ of the breast, the Ductal adenocarcinoma in situ of anogenital MLG is diagnosed. With the location of the tumour in the dermis, its malignancy, invasive histological pattern and architectonics, similar to the architectonics of unspecified breast carcinoma, additionally assess the absence or presence of unspecified breast carcinoma and in its absence, the Ductal adenocarcinoma of the MLG is diagnosed. With the location of the tumour in the dermis, its malignancy, invasive histological pattern and architectonics, similar to the architectonics of tubular-lobular breast carcinoma, additionally assess the absence or presence of tubular-lobular breast carcinoma and, in its absence, the Tubular-lobular carcinoma of the MLG is diagnosed. With the location of the tumour in the dermis, its malignancy, invasive histological pattern and architectonics, similar to the architectonics of adenocystic breast carcinoma, additionally assess the absence or presence of adenocystic carcinoma of the breast and in its absence, the Adenocystic carcinoma of the MLG is diagnosed. When the tumour is located in the epidermis and dermis, its malignancy, the invasive histological pattern in the dermis and the pagetoid histological pattern in the epidermis and architectonics similar to the architectonics of invasive breast carcinoma and Paget's mammary disease, the absence or presence of invasive breast carcinoma and, in its absence Diagnose Extramammary Paget's disease secondary to invasive AMLG carcinoma.

EFFECT: patient is provided with diagnostic clinically-morphological criteria and their combinations for the differential diagnosis of AMPA tumours with increasing sensitivity, specificity, and accuracy of differential diagnosis.

6 dwg, 3 ex