FIELD: biotechnology.
SUBSTANCE: system for creation of bio-engineering models of animal and human tissues is proposed. The system contains a set of gas cylinders with gas mixtures of nitrogen, oxygen and carbon dioxide of a predetermined composition. Each cylinder is connected to a communication system, a culture medium tank, a pump and a heated sealed chamber to accommodate tissue or cell membranes immobilized on the biodegradable carrier. At that, the oxygen content in each cylinder is 1-5%.
EFFECT: invention ensures the reproducibility of optimal conditions for independent formation of tissue structures by cells under the conditions of hypoxia.
2 cl, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| BIOREACTOR | 2013 |
|
RU2525139C1 |
| FLOW-THROUGH BIOREACTOR FOR CULTIVATION OF BIOENGINEERED STRUCTURES | 2018 |
|
RU2789875C2 |
| COMPOSITION FOR PREVENTIVE OR THERAPEUTIC TREATMENT OF CONDITIONS ASSOCIATED WITH CHANGING AMOUNT OF HAIR | 2018 |
|
RU2716159C2 |
| CONDITIONED ENVIRONMENT AND COMPOSITION BASED ON EXTRACELLULAR MATRIX FROM CELLS CULTIVATED IN HYPOXIC CONDITIONS | 2010 |
|
RU2631488C2 |
| METHOD FOR PRODUCTION OF BIOCOMPOSITE SPHEROIDS FOR BONE RESTORATION | 2020 |
|
RU2747087C1 |
| DEVICE AND METHOD FOR AUTOMATED MAINTENANCE OF CONCENTRATION OF DISSOLVED GASES IN CULTURE MEDIUM IN MICROFLUID SYSTEM | 2015 |
|
RU2587628C1 |
| EXTRACELLULAR MATRIX COMPOSITIONS FOR TREATING CANCER | 2009 |
|
RU2523339C2 |
| BIOENGINEERED CONSTRUCT FOR TISSUE IMPLANTATION AND METHOD FOR MAKING SAID BIOENGINEERED CONSTRUCT (VERSIONS) | 2008 |
|
RU2461622C2 |
| TISSUE STRUCTURES OBTAINED BY BIOENGINEERING, AND METHODS FOR THEIR PRODUCTION AND APPLICATION | 2011 |
|
RU2645473C2 |
| METHOD OF GROWING ENAMEL IN EXPERIMENT | 2019 |
|
RU2716485C1 |
