FIELD: medicine.
SUBSTANCE: population groups to be compared are selected. The values of the following laboratory marker indicators of thyroid disorders are determined in each examined person from both groups: free thyroxine (T4); thyroid-stimulating hormone (TSH); antibodies to thyroglobulin (AB to TG); antibodies to thyroid peroxidase (antibodies to TPO). Also, the marker indicators of thyroid gland (TG) ultrasound are determined for the presence or absence of an increase in its volume above/below the physiological norm, a violation of its structure and/or blood flow. For each group, an average value is determined for each marker. For quality indicators, average values are found, taking the "zero" value in the absence of deviations from normal, and the "one" value in the event of deviations from the specified norm. Using the indicated average values for each marker, the contribution of each of them to thyroid disorders formation is determined. To do this, the parabolic law is used to determine the deflection function Fi, where Fi∈[0; 1], for each 1st marker. Each average marker diagnostic index is given an expert weighting factor Ci. The value of the integral index P is computed for the aggregate of these marker indicators for each population group to be compared, according to the claimed formula. Then, the established integral indices are compared for each group, and those that are characterized by a larger value of the integral index are considered to be a group with a higher risk of thyroid disorders formation at the population level.
EFFECT: method allows to conduct an informative and demonstrative comparative integral evaluation of thyroid disorders formation at the population level, to judge the differences in the conditions of impact of various negative factors due to a comprehensive evaluation of the most significant indices.
3 cl, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING THE INDIVIDUAL RISK OF DEVELOPING ENDEMIC GOITER IN HUMANS FOR DIFFERENT LIFE PERIODS | 2017 |
|
RU2658465C1 |
| METHOD OF DIAGNOSTICS OF PHYSICAL DEVELOPMENT DISORDER IN CHILDREN LIVING IN THE CONDITIONS OF COMPLEX LOW-LEVEL POLLUTION OF HABITATS WITH LEAD, MANGANESE, NICKEL, CHROME AND CADMIUM | 2017 |
|
RU2646564C1 |
| METHOD FOR COMPARATIVE INDICATOR EVALUATION AT A POPULATION LEVEL RISK OF FORMATION OF DISORDERS OF FAT AND CARBOHYDRATE METABOLISM IN CHILDREN CONSUMING DRINKING WATER WITH DIFFERENT CONTENT OF ORGANOCHLORINE COMPOUNDS | 2019 |
|
RU2711600C1 |
| METHOD FOR DIAGNOSING DISORDERS OF THE FUNCTIONAL STATE OF THE THYROID GLAND IN CHILDREN 4-10 YEARS OLD LIVING IN THE FAR NORTH | 2022 |
|
RU2794198C1 |
| METHOD FOR PREVENTION AND TREATMENT OF PHYSICAL DEVELOPMENT VIOLATIONS IN CHILDREN ASSOCIATED WITH COMPLEX LOW-LEVEL HABITAT POLLUTION BY LEAD, MANGANESE, NICKEL, CHROMIUM AND CADMIUM | 2017 |
|
RU2639124C1 |
| METHOD FOR ASSESSING CONFORMITY OF THYROID GLAND VOLUME TO NORM OR DEVIATION FROM IT IN CHILDREN ABOVE AVERAGE HEIGHT FROM 4 TO 15 YEARS OLD BY METHOD FOR ULTRASOUND DIAGNOSTICS | 2020 |
|
RU2748514C1 |
| METHOD FOR ASSESSING THE COMPLIANCE OF THE VOLUME OF THE THYROID GLAND WITH THE NORM OR DEVIATION THEREFROM IN 4 TO 15 YEAR OLD CHILDREN WITH A HEIGHT BELOW THE AVERAGE BY MEANS OF ULTRASONIC DIAGNOSTICS | 2020 |
|
RU2756023C1 |
| METHOD FOR DIAGNOSING OF CHRONIC GASTRODUODENITIS IN CHILDREN ASSOCIATED WITH EXPOSURE TO TECHNOGENIC CHROMIUM, NICKEL, MANGANESE, CHLOROFORM AND CARBON TETRACHLORIDE | 2016 |
|
RU2616326C1 |
| METHOD FOR SUBSTANTIATING THE OCCURRENCE OF A NEGATIVE EFFECT IN CHILDREN IN FORM OF A DISEASE ASSOCIATED WITH THE CENTRAL OR AUTONOMIC NERVOUS SYSTEM ASSOCIATED WITH AEROGENIC EXPOSURE OF ALUMINUM | 2017 |
|
RU2666924C1 |
| METHOD FOR STOMACH AND DUODENUM FUNCTIONAL DISORDERS DIAGNOSTICS IN CHILDREN, ASSOCIATED WITH EXPOSURE TO CHROM, NICKEL, MANGANESE AND CHLORORGANIC COMPOUNDS: CHLOROFORM AND TETRACHLOROMETHANE OF TECHNOGENIC ORIGIN | 2016 |
|
RU2618926C1 |
