FIELD: chemistry.
SUBSTANCE: invention relates to a process for the preparation of (E) -2-aryl-8-[aryl (hydroxy) methylene]-8a-hydroxytetrahydropyrrolo [1,2-a] pyrazine-1,6,7 (2H)-trione of the formula below 
, where Ar1= Ph, C6thH5Me-4; Ar2= Ph, C6thH5Cl-4, characterised in that 2-aryl-8-aroyl-3,4-dihydropyrrolo [1,2-A] pyrazine-1,6,7 (2H) -triones are reacted with water in a 1: 1 ratio in an inert aprotic solvent medium, followed by isolation of the desired products.
EFFECT: method has been developed for the preparation of compounds that can be used as starting materials for the synthesis of heterocyclic systems.
3 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| METHOD FOR PRODUCTION OF 2-ARYL-8-PHENYL-3,4,9,14-TETRAHYDROBENZO[B]PYRAZINO[1',2':1,2]PYRROLO[2,3-E][1,4]DIAZEPINE-1,6,7(2H)-TRIONES |
2016 |
- Maslivets Andrej Nikolaevich
- Chervyakov Artem Valentinovich
|
RU2631857C2 |
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2021 |
- Maslivets Andrej Nikolaevich
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- Makhmudov Ramiz Ragibovich
|
RU2763738C1 |
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|
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2012 |
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|
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2013 |
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|
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2023 |
- Maslivets Andrei Nikolaevich
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- Balandina Svetlana Iurevna
|
RU2798423C1 |
| METHOD FOR PREPARATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4,4]NON-2,8-DIENE-4,7-DIONES |
2016 |
- Stepanova Ekaterina Evgenevna
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- Kobelev Aleksandr Ivanovich
- Balandina Svetlana Yurevna
|
RU2631432C1 |
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2013 |
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|
RU2556998C2 |
| 3-(2-ARYL-2,4-DIHYDROXY-1(2-HYDROXYETHYL)-5-OXO-2,5-DIHYDRO-1H-PYRROL-3-YL)QUINOXALINE-2(1H)-ONES HAVING ANALGESIC ACTIVITY AND A METHOD FOR PRODUCTION THEREOF |
2019 |
- Tretyakov Nikita Alekseevich
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|
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2014 |
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|
RU2577523C2 |
