FIELD: chemistry.
SUBSTANCE: invention relates to a process for preparing 4-aroyl-3-hydroxy-1-(2-hydroxyphenyl)-8-thioxo-1,7-diazaspiro[4.4]non-3-ene-2,6-diones, characterised in that 3-aroilpirrolo[2.1-c][1.4]benzoxazine-1,2,4-trione is reacted with a thioacetamide in an inert aprotic solvent, followed by isolation of the desired products. 
Ar = Ph (a, b), C6H4Cl-4 (c), X = h (a, c), Cl (b).
EFFECT: process of preparing compounds having antimicrobial activity.
2 cl, 1 tbl, 4 ex
| Title |
Year |
Author |
Number |
| METHOD FOR PREPARATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4,4]NON-2,8-DIENE-4,7-DIONES |
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|
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2019 |
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