FIELD: chemistry.
SUBSTANCE: invention relates to use of 4-benzoyl-3-hydroxy-1-(2-hydroxyphenyl)-8-thioxo-1,7-diazaspiro[4.4]non-3-ene-2,6-dione of general formula 
, exhibiting antimicrobial activity.
EFFECT: previously unknown antimicrobial activity of 4-benzoyl-3-hydroxy-1-(2-hydroxyphenyl)-8-thioxo-1,7-diazaspiro[4.4]non-3-ene-2,6-dione is revealed.
1 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
| PROCESS FOR THE PREPARATION OF 4-AROYL-3-HYDROXY-1- (2-HYDROXYPHENYL) -8-THIOXO-1,7-DIAZASPIRO [4,4] NON-3-ENE-2,6-DIONES |
2016 |
- Stepanova Ekaterina Evgenevna
- Maslivets Andrej Nikolaevich
- Kobelev Aleksandr Ivanovich
- Balandina Svetlana Yurevna
|
RU2627276C1 |
| 8-HYDROXY-6-(2-HYDROXYPHENYL)-9-AROYL-1-(PHENYLAMINO)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-4,7-DIONES, HAVING ANTIMICROBIAL ACTIVITY |
2024 |
- Mashevskaia Irina Vladimirovna
- Belozerova Dzhamilia Nailevna
- Balandina Svetlana Iurevna
- Sukhanova Polina Vasilevna
|
RU2827550C1 |
| (Z)-9-AROYL-8-HYDROXY-6-(2-HYDROXYPHENYL)-2-(((Z)-2-OXOINDOLIN-3-YLIDENE)HYDRAZONO)-1-THIA-3,6-DIAZASPIRO[4.4 ]NON-8-EN-4,7-DIONES WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Mashevskaya Irina Vladimirovna
- Dmitriev Maksim Viktorovich
- Balandina Svetlana Yurevna
- Lukmanova Dzhamilya Nailevna
|
RU2763739C1 |
| METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES, HAVING ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Balandina Svetlana Yurevna
- Kobelev Aleksandr Ivanovich
- Babikova Natalya Vladimirovna
|
RU2767555C1 |
| METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-3-PHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES HAVING ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Balandina Svetlana Yurevna
- Kobelev Aleksandr Ivanovich
- Babikova Natalya Vladimirovna
|
RU2767558C1 |
| INTERMEDIATE PRODUCTS - METHYL 7-ARYL-4, 9-DIAROYL-3-HYDROXY-1-(2-HYDROXYPHENYL)-2,6-DIOXO-1, 7-DIAZASPIRO[4,4]NONE-3, 8-DIENE-8-CARBOXYLATES; METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4,10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO[6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHOD OF PRODUCING METHYL 6, 9-DIARYL-11-AROYL-2-(O-HYDROXYPHENYL)-3, 4, 10-TRIOXO-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATES; METHYL 11-BENZOYL-2-O-HYDROXYPHEHYL-3, 4, 10-TRIOXO-9-P-TOLYL-6-PHENYL-7-OXA-2, 9-DIAZATRICYCLO [6.2.1.0]UNDEC-5-ENE-8-CARBOXYLATE HAVING ANTIMICROBIAL ACTIVITY |
2008 |
- Racheva Nadezhda L'Vovna
- Maslivets Andrej Nikolaevich
- Aleksandrova Galina Arsent'Evna
|
RU2383550C1 |
| METHOD FOR PRODUCING 3-AROYL-4-HYDROXY-1-(2-HYDROXYARYL)-1',3'-DIMETHYLSPIRO[PYRROLE-2,5'-PYRROLO[2,3-d]PYRIMIDINE]-2',4', 5,6'(1H,1'H,3'H,7'H)-TETRAONES WITH ANTIMICROBIAL ACTIVITY |
2023 |
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
- Kobelev Aleksandr Ivanovich
|
RU2806039C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-[2-(HYDROXYMETHYL)PHENYL]-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONE AS AN AGENT HAVING ANTIMICROBIAL ACTIVITY |
2022 |
- Maslivets Anna Andreevna
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
- Muliukova Alina Borisovna
- Andreeva Anastasiia Aleksandrovna
- Poturaev Petr Sergeevich
|
RU2790482C1 |
| APPLICATION OF 2-[(R-BENZYLIDENE)HYDRAZONO]-8-HYDROXY-6-(2-HYDROXYPHENYL)-9-AROYL-1-THIA-3,6-DIAZASPIRO[4.4]NONA-8-EN-4,7-DIONES AS AGENTS WITH ANTI-INFLAMMATORY ACTIVITY |
2022 |
- Mashevskaia Irina Vladimirovna
- Lukmanova Dzhamilia Nailevna
- Apushkin Danila Iurevich
- Utushkina Taisiia Andreevna
- Iakushina Karolina Evgenevna
- Andreev Aleksandr Igorevich
|
RU2783241C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIALKYL-2-THIOXO-1,3,6-TRIAZASPIRO[4.4 NON-8-ENE-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Balandina Svetlana Yurevna
|
RU2763731C1 |
