FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 9-aroyl-8-hydroxy-6-(2-hydroxyaryl)-1,3-diphenyl-1,3,6-triazaspiro[4.4]non-8-ene-2,4,7-triones of formula IIa-b by reacting 3-aroylpyrrolo[2,1-c][1,4]benzoxazine-1,2,4-triones of formula Ia-b with diphenylurea, carried out by boiling reagents in toluene according to the following scheme
, where I and II: Ar=Ph, R=Cl (a); Ar=C6H4Cl-4, R=H (b).
EFFECT: developed the method of producing 9-aroyl-8-hydroxy-6-(2-hydroxyaryl)-1,3-diphenyl-1,3,6-triazaspiro[4_4]non-8-ene-2,4,7-triones with antimicrobial activity.
1 cl, 1 tbl, 3 ex
| Title |
Year |
Author |
Number |
| METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-3-PHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES HAVING ANTIMICROBIAL ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Balandina Svetlana Yurevna
- Kobelev Aleksandr Ivanovich
- Babikova Natalya Vladimirovna
|
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2022 |
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
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|
RU2785344C1 |
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2023 |
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|
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|
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2016 |
- Stepanova Ekaterina Evgenevna
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|
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2021 |
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2016 |
- Stepanova Ekaterina Evgenevna
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|
RU2631432C1 |
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2021 |
- Maslivets Andrej Nikolaevich
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|
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2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2790379C1 |
