FIELD: organic chemistry; pharmaceuticals; analgesics.
SUBSTANCE: following is disclosed: the use of 9-aroyl-8-hydroxy-6-(2-hydroxyaryl)-2-thioxo-1,3,6-triazaspiro[4.4]non-8-ene-4,7-diones of general formula 1 as agents having analgesic activity.
1
Ar = Ph, R = H (a), Ar = Ph, R = Cl (b), Ar = 4-BrC6H4, R = H (c).
EFFECT: invention provides an effective analgesic effect.
1 cl, 1 tbl, 4 ex
Title |
Year |
Author |
Number |
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