USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-4,7-DIONES AS AGENTS WITH ANALGESIC ACTIVITY Russian patent published in 2023 - IPC A61K31/4188 C07D487/10 A61P29/00 

Abstract RU 2810074 C1

FIELD: organic chemistry; pharmaceuticals; analgesics.

SUBSTANCE: following is disclosed: the use of 9-aroyl-8-hydroxy-6-(2-hydroxyaryl)-2-thioxo-1,3,6-triazaspiro[4.4]non-8-ene-4,7-diones of general formula 1 as agents having analgesic activity.

1

Ar = Ph, R = H (a), Ar = Ph, R = Cl (b), Ar = 4-BrC6H4, R = H (c).

EFFECT: invention provides an effective analgesic effect.

1 cl, 1 tbl, 4 ex

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RU 2 810 074 C1

Authors

Maslivets Andrei Nikolaevich

Kobelev Aleksandr Ivanovich

Makhmudov Ramiz Ragibovich

Dates

2023-12-21Published

2023-03-30Filed