FIELD: pharmacology.
SUBSTANCE: invention relates to the use of 4-((pyridin-2-yl)-diazenyl) phenylsulfonic acid derivatives and their salt forms of general formula I:
,
where R1=R2=H, or R1 and R2 together form a substituent of the form CR3R4, where R3=H, CH3, R4=H, CH3, C2H5, i-C3H7, C7H15, C8H17, or R4 R5 together form a spirocycloalkyl group, where R3, R4 = cyclo-C5H8, cyclo-C6H10; X+ = H, alkali and alkaline earth metal cations, such as Na+, K+, Mg2+, Ca2+ et al, NH4+ and other pharmaceutically acceptable cations of organic and inorganic nature, as inhibitors of final glycation products (FGP) formation.
EFFECT: improved compounds properties.
2 tbl, 1 ex
| Title | Year | Author | Number |
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| INHIBITORS OF FORMATION OF GLYCATION END PRODUCTS BASED ON AZO-DERIVATIVE PHENYLSULPHONIC ACIDS | 2016 |
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|
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| SODIUM SALT OF 3-NITRO-4-OXO-1,4-DIHYDROPYRAZOLO[5,1-c]-1,2,4-TRIAZINE-8-CARBOXYLIC ACID, DIHYDRATE | 2016 |
|
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| SODIUM SALT OF DIETHYL ETHER OF 4-OXO-1,4-DIHYDROPYRAZOLO[5,1-C]-1,2,4-TRIAZINE-3,8-DICARBOXYLIC ACID MONOHYDRATE | 2015 |
|
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| PHARMACEUTICAL COMPOSITION OF ANTIGLYCATING ACTIVITY IN SOLID DOSAGE FORM IN FORM OF CAPSULES AND METHOD FOR PREPARATION THEREOF | 2019 |
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| BIS[1,2,4]TRIAZOLO[4,3-b:3',4'-f][1,2,4,5]TETRAZINES WITH ANTI-GLYCATING, ANTI-GLYCOXIDATION AND ANTIPLATELET ACTIVITY | 2020 |
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| QUATERNARY AMMONIUM SALTS BASED ON DERIVATIVES OF VITAMIN B6 | 2015 |
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