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2 738 804

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IPC

A61K31/53(2006-01-01)

A61P3/10(2006-01-01)

(21) (22)

Application

2019122542, 2019-07-15

(24)

Start date

2019-07-15

(22)

Actual filing date

2019-07-15

(45)

Published

2020-12-17

(72)

Inventor

Kosolapov Vadim AnatolevichKotovskaya Svetlana KonstantinovnaPetrov Vladimir IvanovichRusinov Vladimir LeonidovichSapozhnikova Irina MikhajlovnaSmirnova Lyudmila AndreevnaSpasov Aleksandr AlekseevichStepanova Eleonora FedorovnaShevchenko Aleksandr Mikhajlovich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Federalnyj Universitet Imeni Pervogo Prezidenta Rossii B.N. Eltsina"Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

PHARMACEUTICAL COMPOSITION OF ANTIGLYCATING ACTIVITY IN SOLID DOSAGE FORM IN FORM OF CAPSULES AND METHOD FOR PREPARATION THEREOF Russian patent published in 2020 - IPC A61K31/53 A61P3/10

Abstract RU 2738804 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to pharmacology and pharmacy and concerns production of an antiglycating agent. Such agent is a pharmaceutical composition in a solid dosage form for oral administration, containing as an active ingredient sodium salt of diethyl ether 4-oxo-1,4-dihydropyrazolo[5,1-c]-1,2,4-triazin-3,8 -dicarboxylic acid monohydrate, with the following ratio of components, wt. %: sodium salt of diethyl ether of 4-oxo-1,4-dihydropyrazolo[5,1-c]-1,2,4-triazine-3,8-dicarboxylic acid monohydrate 95–97.0 %; Plasdone K-29/32 1–5 %; magnesium stearate not more than 1 %.

EFFECT: composition provides an antiglycating effect by inhibiting effect on end glycation products of collagen.

3 cl, 7 dwg, 2 ex

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RU 2 738 804 C1

Authors

Kosolapov Vadim Anatolevich

Kotovskaya Svetlana Konstantinovna

Petrov Vladimir Ivanovich

Rusinov Vladimir Leonidovich

Sapozhnikova Irina Mikhajlovna

Smirnova Lyudmila Andreevna

Spasov Aleksandr Alekseevich

Stepanova Eleonora Fedorovna

Shevchenko Aleksandr Mikhajlovich

Dates

2020-12-17—Published

2019-07-15—Filed