SOFT CHEWING PHARMACEUTICAL PRODUCTS Russian patent published in 2017 - IPC A61K9/68 A61K47/12 

FIELD: pharmacology.

SUBSTANCE: method of manufacturing a soft chewable veterinary pharmaceutical product containing as ingredients: an isoxazoline compound, pamoic acid or a pharmaceutically acceptable salt thereof, a liquid component, a forming agent and optionally one or more excipients in a forming machine, comprises mixing the ingredients into a dough Mixing dry ingredients, followed by the addition of liquid components to form a thoroughly mixed mixture, unloading the dough-like mass from that the mixer into a suitable container for further manufacturing individual dosage units by using a moulding machine, mould filling doughy mass and removing dough from the mould, wherein the mixing step, from 1.5 to 30% of pamoic acid or a pharmaceutically acceptable salt or pamoate salt of the active pharmaceutical ingredient is mixed with the other ingredients. The pharmaceutically acceptable salt of the pamoic acid is sodium pamoate. The soft chewable pharmaceutical product obtained by the process of the invention is used in the manufacture of a medicament for controlling the infection of an animal with parasitic insects or acarids.

EFFECT: method of manufacturing a soft chewable veterinary pharmaceutical product provides ease in the manufacture of the product.

9 cl, 7 tbl, 4 ex