METHOD OF EXPRESS DETERMINATION OF CARDIOMYOGLOBIN IN BLOOD PLASMA USING ELECTROCHEMICAL SENSOR BASED ON CARBON NANOTUBES AND MOLECULAR IMPRINTED POLY-O-PHENYLENEDIAMINE AS BIOAFFINITY REAGENT Russian patent published in 2017 - IPC G01N27/327 

FIELD: medicine.

SUBSTANCE: method for express determination of myoglobin in blood plasma by an electrochemical sensor includes application of 2 mcl of a plasma sample to the surface of a working electrode previously modified with a carbon nanotubes suspension, followed by modification of the obtained electrode by o-phenylenediamine electropolymerization in the presence of myoglobin carried out on the electrode surface and subsequent removal of the myoglobin template, maintaining of the sensor with the sample for 15 minutes at ±371°C, electrochemical recording of hemoprotein by measuring the height of the heme iron reduction peak by differential pulse voltammetry and determination of myoglobin content in the sample is determine from the previously obtained calibration schedule.

EFFECT: increased accuracy of determination.

2 dwg, 1 tbl, 3 ex