AQUEOUS OPHTHALMIC SOLUTION BASED ON CYCLOSPORIN A Russian patent published in 2017 - IPC A61K9/08 A61K38/13 A61K47/14 A61K47/32 A61K47/38 A61P27/02 

FIELD: pharmacology.

SUBSTANCE: stable aqueous ophthalmic solution contains an immunosuppressive agent, a cellulose derivative as the first polymer, a polyvinyl derivative as the second polymer, and a lipophilic functional polymer as the third polymer. This solution does not contain an organic solvent, an antimicrobial preservative and does not actually contain particles. To produce the said solution, an immunosuppressant is solubilized in the presence of at least a portion of the first polymer, in the presence of water; any remaining part of the first polymer is mixed with two other polymers, water and optionally buffer systems and isotonic agents; and the products obtained in the previous steps are mixed. For treatment of disorders associated with the eye surface, having an inflammatory-immune base, the said solution is administered to humans or animals.

EFFECT: effective treatment of ophthalmic diseases of inflammatory-immune genesis.

17 cl, 3 dwg, 3 tbl, 6 ex