METHOD FOR PERFORMING LOW-FREQUENCY PIEZOTHROMBOELASTOGRAPHY IN SMALL LABORATORY ANIMALS Russian patent published in 2017 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention is designed to perform low-frequency piezothromboelastography under the normal condition, under the pathological condition, and when modeling pathology in small laboratory animals on the hardware and software complex for clinico-diagnostic studies of rheological blood properties ARP-01M Mednord using an information-computer system (ICS) Hemo-3. The method is the recording of the curve of low-frequency piezothromboelastography using the amplitude delta in the Hemo-3 ICS settings to accept a maximum point equal to 1 and the waiting time of an amplitude increase equal to 20 minutes and allows to determine such indicators as contact coagulation intensity (CCI), time of contact coagulation t₁, coagulation drive intensity (CDI), thrombin constant achievement time t₂, thrombin activity constants (TAC), clotting time t₃, clot polymerization intensity (CPI), polymerization time t₄, maximum clot amplitude (MCA), formation time of the fibrin-thrombocytic structure t₅, total coagulation intensity (TCI), intensity of lysis and clot retraction (ILCR), t₆=t₅+10 minutes, total anticoagulative activity coefficient (TAAC).

EFFECT: improved accuracy and reliability.

2 dwg