METHOD FOR TESTING ANTICOAGULANT ACTIVITY OF BLOOD Russian patent published in 2014 - IPC G01N33/49 

Abstract RU 2530584 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to testing the anticoagulant activity of blood. Substance of the method consists in performing low-frequency piezothromboelastography and measuring blood viscosity characteristics: A0 is an initial blood state of aggregate, A1 is a value describing the maximum change of the blood state of aggregate at the stage of contact activation, A3 is a value describing the blood state of aggregate at the stage of the beginning of the polymerization process, t3 is the time to reach A3, A4 is a value describing the blood state of aggregate 10 min after the A3 value is achieved, t4 is always 10 minutes, as well as a clot polymerisation intensity (CPI); a coefficient of the anticoagulant activity of blood (AAB) is calculated by formula. If the AAB value falls within the range of 1.5-2, the normal anticoagulant activity is stated, while the AAB values less than 1.5 shows the decreased anticoagulant activity.

EFFECT: using the method enables monitoring the anticoagulant activity of blood both at the stage of diagnosing, and at any stage of therapy of haemostatic disorders with high accuracy and reliability by carrying out the integrated assessment of the anticoagulant activity of blood.

1 tbl, 1 dwg, 2 ex

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RU 2 530 584 C2

Authors

Tjutrin Ivan Illarionovich

Shpisman Mikhail Natanovich

Klimenkova Valentina Fedorovna

Bochkov Jurij Aleksandrovich

Dates

2014-10-10Published

2012-12-20Filed