METHOD FOR DETERMINING AN ANTICOAGULANT POTENTIAL OF A VASCULAR WALL Russian patent published in 2019 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to laboratory diagnostics, and can be used to determine an anticoagulant potential of a vascular wall. That is ensured by double blood viscosity assessment by low-frequency piezocutaneous elastography (LPTEG) before and after dissolving an aliquot of whole blood 0.9 % with normal saline. Parameters of the LPTEG curve are determined: A1₁ – index of the minimum level of whole blood plasma LPTEG amplitude, where t1₁ is its reaching time; t3₁ is the time of achieving a gelation point in whole blood – the beginning of the fibrin polymerisation stage; A1₂ is an index of a minimum level of the curve of the LPTEG after adding an aliquot of whole blood to physiological solution, where t1₂ is its reaching time; t3₂ is the time of reaching the blood jellying point – the beginning of the fibrin polymerisation stage. If values A1₂ lower than A1₁, and if value t1₂, t3₂ greater than t1₁, t3₁ anticoagulant potential of the vascular wall is defined as normal. If values A1₂ higher than A1₁, and if value t1₂, t3₂ less than t1₁, t3₁, anticoagulant potential of the vascular wall is defined as reduced.

EFFECT: invention enables determining the anticoagulant potential of a vascular wall in a patient.

1 cl, 4 dwg, 2 ex