BIO-ENGINEERING STRUCTURE WITH ANTIBACTERIAL COATING FOR OSTEOCHONDRAL DEFECTS SUBSTITUTION Russian patent published in 2017 - IPC A61F2/28 A61L27/56 A61L27/14 A61L27/28 

Abstract RU 2634860 C1

FIELD: medicine.

SUBSTANCE: bioengineering multilayer structure based on biocompatible ultra-high molecular weight polyethylene contains a porous layer that can be populated with multipotent mesenchymal stromal cells of mammals and a continuous layer with an antibacterial coating based on amoxicillin 0.1-5 mm. The porous layer has an open porosity of up to 90 vol. % and a bound pore system with a diameter of 30-1000 mcm.

EFFECT: application of the invention provides a bioengineering structure that imitates the structure of cortical and trabecular tissues of the native bone and prevents development of local infectious complications in the postoperative period.

3 cl, 3 dwg, 2 ex

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RU 2 634 860 C1

Authors

Maksimkin Aleksej Valentinovich

Senatov Fedor Svyatoslavovich

Anisimova Natalya Yurevna

Kiselevskij Mikhail Valentinovich

Zalepugin Dmitrij Yurevich

Tilkunova Nataliya Aleksandrovna

Chernyshova Irina Valerevna

Kaloshkin Sergej Dmitrievich

Dates

2017-11-07Published

2016-12-19Filed