FIELD: biotechnology.
SUBSTANCE: inventions relate to antimicrobial peptides selected and purified from extracts of tilapia gill (Oreochromis niloticus), and also methods and compositions in which they can be used. The presented peptides can be obtained by chemical synthesis or expression in a heterologous system, such as bacteria and yeast, using conventional molecular-biological techniques. Peptides have antimicrobial activity against various organisms, including gram-positive bacteria, gram-negative bacteria, fungi and viruses.
EFFECT: inventors can effectively enhance the immune response induced by various antigens, and monitor the progression of diseases caused by pathogens.
16 cl, 9 dwg, 1 tbl, 10 ex
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