MEANS FOR BIOLOGICALLY ACTIVE SUBSTANCES DELIVERY TO BODY CELLS AND TISSUES AND ITS APPLICATION Russian patent published in 2017 - IPC A61K31/00 A61K47/34 

FIELD: pharmacology.

SUBSTANCE: group of inventions refers to means for biologically active substances delivery to body cells and tissues, obtained by oxidation of either a block copolymer with the structure

of ,

x=8.1; y=27.8, while the degree of modification of the block copolymer terminal hydroxyl groups to carboxylic group is 80%; or of a block copolymer with the structure of

,

where x=2.3; y=31, while the degree of modification of the block copolymer terminal hydroxyl groups to carboxylic group is 67%, and to application of these means in a composition with an active ingredient to enhance the active substance delivery to human cells and increase cells sensitivity to the active substance effect or to increase tissues permeability to the active substance.

EFFECT: reduced susceptibility to aggregation in physiological conditions and a higher ability to deliver biologically active substances through the membrane into human cells.

4 cl, 4 dwg, 1 tbl, 10 ex