METHOD OF PRODUCING CHALATE CISS-S,S-COMPLEXES OF DIACETATE(DIBROMIDE)[DI-1,6-(3,5-DIMETHYLIZOXAZOLE-4-IL)-2,5-DITIAHEXANE]PALLADIUM (II) Russian patent published in 2017 - IPC C07F15/00 C07D261/08 A61K31/555 B01J31/22 

Abstract RU 2637943 C1

FIELD: chemistry.

SUBSTANCE: invention refers to the chemistry of coordination compounds, in particular to the method of producing chelate CIS-S,S-complexes of diacetate(dibromide)[di-1,6-(3,5-dimethylizoxazole-4-yl)-2.5-ditiahexane]palladium(II) of the common formula

(1) X=X'=CH3COO, Br. The method includes the interaction of the bidentate reagent of 1,2-bis[sulfanilate(3,5-dimethylisoxazole-4-yl)]ethane with diacetate (dibromide) palladium(II) in the environment of acetonitrile in the molar ratio of bis[sulfanilate(3,5-dimethylisoxazole-4-yl)]ethane: diacetate (dibromide) palladium(II) equal to 1:1, at a temperature of 15-25°C and atmospheric pressure for 3-5 hours.

EFFECT: resulting compounds can find application as biologically active substances with an anticancer activity and catalysts of chemical reactions.

1 tbl, 6 ex

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RU 2 637 943 C1

Authors

Akhmetova Vnira Rakhimovna

Akhmadiev Nail Salavatovich

Khisamutdinov Ravil Akhmetzyanovich

Ibragimov Askhat Gabdrakhmanovich

Dzhemilev Usein Memetovich

Dates

2017-12-08Published

2016-06-17Filed