METHOD FOR TREATING ANAL FISSURE CASES Russian patent published in 2008 - IPC A61K31/21 A61K31/125 A61K31/5375 A61K38/08 A61P43/00 

FIELD: medicine.

SUBSTANCE: method involves carrying out histological study of smear imprint, bioptate or operation preparation. Histological picture corresponding to the first stage of wound process, conservative therapy course is to be complemented with peroral introduction of Pinaverium bromide at a dose of 50 mg thrice a day 10 days long and local transanal instillations 2 ml 0.1% glycerol trinitrate solution twice a day 6 weeks long. Conservative therapy course at the second stage of wound process is to be complemented with Mebeverine hydrochloride at a peroral dose of 200 mg thrice a day 2 weeks long and intramuscular introduction of Dalargin at a dose of 1 mg twice a day 2 weeks long. Conservative therapy course at the third stage of wound process is to be complemented with Mebeverine hydrochloride at a peroral dose of 200 mg twice a day 2 weeks long and intramuscular introduction of Dalargin at a dose of 2 mg twice a day 2 weeks long and local transanal instillations with 2 ml 0.1% glycerol trinitrate solution twice a day 4 weeks long. Conservative therapy course at the second and the third stage of wound process is also to be complemented with peroral introduction of nonsteroid anti-inflammatory means.

EFFECT: enhanced effectiveness of treatment when applied as rational drug the in postoperative period; accelerated rehabilitation; reduced frequency of disease recurrence.