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(19)

(11)

2 639 875

(13)

(51)

IPC

C07D207/12(2006-01-01)

C07D211/44(2006-01-01)

C07D211/48(2006-01-01)

C07D211/52(2006-01-01)

A61K31/40(2006-01-01)

A61K31/451(2006-01-01)

A61P3/00(2006-01-01)

A61P9/00(2006-01-01)

A61P13/00(2006-01-01)

A61P27/02(2006-01-01)

A61P35/00(2006-01-01)

A61P37/02(2006-01-01)

(21) (22)

Application

2015145460, 2014-03-25

(24)

Start date

2014-03-25

(22)

Actual filing date

2014-03-25

(45)

Published

2017-12-25

(72)

Inventor

Kusumi KensukeNaganava AtsusiOtsuki KazukhiroSekiguti TetsuyaSinodzaki KodziYamamoto KhirosiYamamoto Yasuko

(73)

Holder

Ono Farmasyutikal Ko., Ltd.

PHENYL DERIVATIVE Russian patent published in 2017 - IPC C07D207/12 C07D211/44 C07D211/48 C07D211/52 A61K31/40 A61K31/451 A61P3/00 A61P9/00 A61P13/00 A61P27/02 A61P35/00 A61P37/02

Abstract RU 2639875 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to a compound of the general formula (I) having a high antagonistic activity with respect to human S1P₂, and can be used to prepare a drug for treatment of a disease mediated by S1P₂, such as a disease caused by vasoconstriction, fibrosis and respiratory disease.

EFFECT: compound application efficiency increase.

14 cl, 2 tbl, 9 ex

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RU 2 639 875 C2

Authors

Kusumi Kensuke

Naganava Atsusi

Otsuki Kazukhiro

Sekiguti Tetsuya

Sinodzaki Kodzi

Yamamoto Khirosi

Yamamoto Yasuko

Dates

2017-12-25—Published

2014-03-25—Filed