METHOD FOR OBTAINING OF COMPOSITION BASED ON HYALURONIC ACID Russian patent published in 2018 - IPC A61K9/10 A61K47/36 A61L27/20 A61L27/26 A61F2/02 

FIELD: cosmetology.

SUBSTANCE: invention is a process for preparation of a composition for use as a dermatological excipient in cosmetic and medical applications in the form of a gel comprising a crosslinked first polymer, optionally a second polymer that can be crosslinked or uncross linked, and water, wherein the first and second polymers are selected from polysaccharide, and the process comprises at least steps (i), (ii) and (iv), and optionally step (iii), wherein step (i) is to crosslink a mixture including the first polymer and water, step (ii) is to finish the crosslinking of step (i), step (iii) is to optionally blend the product obtained in step (ii) with the second polymer, step (iv) consists in dialysis of the product obtained in step (ii) or in step (iii), wherein the dialysis step (iv) comprises steps (iv.1)-(iv.3)(iv.1) which is extrusion of the product, obtained in step (ii) or (iii) through the first sieve and then extrusion of the product extruded through the first sieve through the second sieve, in which the second sieve hole size is smaller than the first sieve hole size; or extrusion of the product, obtained in step (ii) or (iii) through the first sieve and then extrusion of the product extruded through the first sieve through the second sieve, and then extrusion of the product extruded through the second sieve through the third sieve, in which the second sieve hole size is smaller than the first sieve hole size, and the third sieve hole size is smaller than the second sieve hole size, where step (iv.2) is to fill the dialysis membrane with the product obtained in step (iv.1), step (iv.3) is to process the filled membrane obtained in step (iv.2) with dialysis solution.

EFFECT: obtaining of exclusively homogeneous compositions.

14 cl, 14 ex