FIELD: chemistry.
SUBSTANCE: method involves obtaining a substrate of hyaluronic acid dissolved in the first liquid medium, which is an aqueous solution, without any stitching, the deposition substrate of hyaluronic acid, subjecting it to the influence of the second liquid medium containing one or more first water-soluble organic solvent in an amount to provide the conditions for the deposition of hyaluronic acid without any stitching. In these steps, the desired shape in the form of particles, fibres, a tape, a filament, a mesh, a film, a disc or granules is imparted to the hyaluronic acid substrate. Then the precipitated substrate of non-cross-linked hyaluronic acid in the desired form is subjected to the single-stage of cross-linking in the third liquid medium under the conditions suitable for obtaining a moulded product precipitated from cross-linked hyaluronic acid. The third liquid medium has a pH of 11.5 or higher and contains one or more polyfunctional cross-linking agents and a quantity of one or more second organic solvents to ensure conditions of hyaluronic acid deposition. Moulded products from cross-linked hyaluronic acid, an aqueous composition containing one of these products and the use of a moulded product or aqueous composition in a cosmetic surgical procedure are also provided.
EFFECT: invention allows to obtain a moulded product from cross-linked hyaluronic acid with a high resistance to deformation.
31 cl, 6 dwg, 11 tbl, 13 ex
