FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine. There are described soft tissue fillers, such as cutaneous and subcutaneous fillers based on hyaluronic acids and pharmaceutically acceptable salts thereof. What is described is a hyaluronic acid composition which contains a therapeutically effective amount of at least one analgesic agent, e.g., lidocaine, and additionally non-cross-linked hyaluronic acid. There are also described the methods for preparing the hyaluronic acid compositions.
EFFECT: hyaluronic acid composition containing lidocaine has improved stability as compared to conventional lidocaine compositions, eg having been sterilised or stored for long periods of time.
12 cl, 1 dwg, 3 tbl, 4 ex
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