FIELD: medicine.
SUBSTANCE: method is proposed for obtaining of DNA primers and probes to determine the presence and the relative amount of fetal DNA in a plasma sample of a pregnant woman. A method and a set are proposed to determine the presence and concentration of fetal DNA in a plasma sample of a woman.
EFFECT: effective detection of primer structures corresponding to the differentially methylated regions of the mother and fetus DNA.
17 cl, 1 dwg, 4 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING DNA PRIMERS AND PROBES FOR MINIMALLY INVASIVE PRENATAL PCR DIAGNOSIS OF TRISOMY OF 21ST CHROMOSOME OF FETUS IN BLOOD OF PREGNANT WOMAN AND DIAGNOSTIC KIT THEREFOR | 2014 |
|
RU2602366C2 |
| NONINVASIVE DIAGNOSTIC DNA TEST FOR ANEUPLOIDY DETECTION | 2012 |
|
RU2638456C2 |
| METHOD FOR NON-INVASIVE PRENATAL DIAGNOSTICS OF TRISOMY AND A SET FOR IT | 2020 |
|
RU2734484C1 |
| PREDICTION OF PREECLAMPSIA BASED ON DETERMINING EXTRACELLULAR FETAL DNA IN MATERNAL BLOOD WHEN SCREENING THE FIRST TRIMESTER OF PREGNANCY | 2019 |
|
RU2697845C1 |
| METHOD FOR PREDICTION OF PLACENTAL INSUFFICIENCY DEVELOPMENT | 2017 |
|
RU2703463C2 |
| METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING | 2011 |
|
RU2671980C2 |
| METHOD FOR NONINVASIVE PRENATAL DIAGNOSTICS OF FETAL ANEUPLOIDY | 2015 |
|
RU2627673C2 |
| HIGHLY MULTIPLEX PCR METHODS AND COMPOSITIONS | 2012 |
|
RU2650790C2 |
| METHODS OF NONINVASIVE PRENATAL PATERNITY DETERMINATION | 2011 |
|
RU2620959C2 |
| METHOD FOR PREDICTING NEWBORN WEIGHT IN PREGNANT WOMEN WITH PREECLAMPSIA IN COMBINATION WITH FETAL GROWTH RETARDATION SYNDROME | 2020 |
|
RU2741861C1 |
