FIELD: biotechnology.
SUBSTANCE: benzoilamino (phenylsulfonyl)-substituted cyclic amino acids of the general formula 
where R1, R2, R3, R4, R5, R6, R7 may be hydrogens, halogen atoms, (C1-C4)-alkyl groups, nitro groups; "n" can be 1-3, and their physiologically acceptable salts which are inhibitors of zinc-dependent metalloproteinases (MMP-2 and MMP-9). Also a method for preparation of compounds of formula (1) and a method for treating by remodelling of the left ventricle of the heart in the peracute phase of myocardial infarction using compounds of the formula (1) are provided.
EFFECT: increased efficiency of treatment.
4 cl, 3 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| INHIBITOR OF MATRIX METALLOPROTEINASES OF 2nd AND 9th TYPES FROM SERIES OF BENZOYLAMINO(PHENYLSULPHONYL)-L-OXYPROLINE DERIVATIVES, HAVING NEUROPROTECTIVE AND ANTICANCER ACTIVITY | 2023 |
|
RU2826902C1 |
| ANTHRANILIC ACID DERIVATIVE HAVING ANTIHYPOXIC, ANALGESIC AND MNEMOTROPIC ACTIVITY | 2023 |
|
RU2820516C1 |
| DERIVATIVES OF 2-SUBSTITUTED PHENYL-5,7-DIHYDROCARBYL-3,7-DIHYDROPYRROLO[2,3-d]PYRIMIDIN-4-ONES, THEIR PREPARING AND PHARMACEUTICAL USING | 2004 |
|
RU2323220C2 |
| 1H-PYRROLO[3,4-b]QUINOLINE-3,9(2H,4H)-DIONES EXHIBITING ANTI-TUBERCULOSIS ACTIVITY AND METHOD FOR PREPARING THEM | 2009 |
|
RU2457208C2 |
| 11b-(HET)ARYL-2,3,611b-TETRAHYDROOXAZOLO[2',3':2,1]PYRROLO[3,4-b]QUINOLIN-5,11-DIONES AND SYNTHESIS METHOD THEREOF | 2007 |
|
RU2381229C2 |
| BIS(METOXYBENZYLAMINOALKYL)AMINES WITH CARDIOTROPIC ACTIVITY | 2014 |
|
RU2624438C2 |
| PYRROLOCHINOLINE DERIVATIVES AS 5-HT ANTAGONISTS, METHODS FOR PRODUCTION THEREOF AND USE | 2013 |
|
RU2688161C2 |
| USING EP4 RECEPTOR LIGANDS IN TREATMENT OF IL-6-MEDIATED DISEASES | 2003 |
|
RU2285527C2 |
| METHOD FOR PRODUCING SUBSTITUTED 3-ARYL-5-CHLOROSOXAZOLES | 2015 |
|
RU2637927C2 |
| DERIVATIVES OF ANTHRANILIC ACID OR THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS, INTERMEDIATE COMPOUNDS USED FOR THEIR SYNTHESIS AND DRUG | 1994 |
|
RU2128644C1 |
