FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to cardiac surgery, and concerns treatment of ventricular arrhythmias. For this purpose, a pharmaceutical composition containing botulinum neurotoxin type A is introduced into the foci of ectopic excitation of the ventricular myocardium. Composition is administered in a volume of 0.2-0.4 ml with a botulinum neurotoxin content in the total dose of 0.5-0.9 U/kg. Administration is performed during an operation that is performed by median sternotomy or by a minimally invasive intramyocardial route.
EFFECT: method provides denervation of foci of ectopic myocardium excitation and, accordingly, effective treatment or prevention of ventricular tachycardia and ventricular fibrillation in patients who are contraindicated with radiofrequency ablation of the myocardium.
3 cl, 2 dwg, 2 ex
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