OPTICAL BIOSENSOR OF IRREVERSIBLE INHIBITORS OF CHOLINESTERASE IN THE AIR Russian patent published in 2018 - IPC G01N21/76 C12Q1/46 

FIELD: meteorology.

SUBSTANCE: invention relates to the control of air environment contamination. Optical biosensor in the air includes: an optical detector and an active component consisting of an immobilized fluorescent cholinesterase complex with a reversible inhibitor – a fluorogenic agent, the fluorescence intensity of which decreases in the presence of an irreversible inhibitor with the formation of an analytical signal – a decrease in the fluorescence intensity of the active component of the biosensor. Active component of the optical biosensor consists of a cholinesterase complex with a reversible inhibitor, the fluorogenic agent – ethidium bromide, immobilized by the sol-gel method.

EFFECT: technical result consists in increasing the sensitivity of the optical biosensor to irreversible inhibitors of cholinesterase, as well as in increasing the rate of formation of the analytical signal.

3 cl, 6 dwg, 2 tbl