MEANS AND METHOD FOR EARLY EXPERIMENTAL CONTRAST MAGNETIC-RESONANCE TOMOGRAPHIC DETECTION OF MALIGNANT GLIAL TUMORS WITH FEEDING VESSELS Russian patent published in 2018 - IPC A61K49/00 A61K49/06 A61B5/55 B82B3/00 

Abstract RU 2655303 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to experimental medicine and discloses a method for producing cobalt-doped dextranferrites, as well as a method for early detection of vessels feeding a tumor. These methods allow selectively increasing the number of pixels for early contrast MRT imaging of weighted 3D contrast MRT images by lowering the signal of protons of normal tissues to a hypointense and increasing the signal of protons of tumor glial tissues with feeding vessels to hyperintense 3–4 days after inoculation, which is 3–4 days earlier than the known methods for detecting glial tumors, and can be used for early experimental contrast MRT detection of malignant glial tumors with vessels feeding them.

EFFECT: these methods allow selectively increasing the number of pixels for early contrast MRT imaging of weighted 3D contrast MRT images.

4 cl, 16 dwg, 5 ex, 4 tbl

Similar patents RU2655303C2

Title Year Author Number
AGENT FOR EARLY CONTRAST DETECTION OF MALIGNANT PROLIFERATION CENTERS WITH FEEDING VESSELS, BOUNDARIES OF DIFFUSE INFILTRATION AND DETERMINATION OF STAGES OF THEIR DEVELOPMENT IN DYNAMICS 2017
  • Brusentsov Nikolaj Antonovich
  • Golubeva Irina Sergeevna
  • Borisova Larisa Mikhajlovna
  • Bocharova Olga Alekseevna
  • Pirogov Yurij Andreevich
  • Anisimov Nikolaj Viktorovich
  • Gulyaev Mikhail Vladimirovich
RU2692579C2
MEANS AND METHOD FOR COMBINED CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING IMAGE VISUALIZATION OF BIOMECHANICS OF THE PROCESSES OF INFILTRATION, INVASION AND METASTASIS OF MALIGNANT CELLS 2020
  • Brusentsov Nikolaj Antonovich
  • Polyanskij Vitalij Aleksandrovich
  • Golubeva Irina Sergeevna
  • Pirogov Yurij Andreevich
  • Gulyaev Mikhail Vladimirovich
  • Anisimov Nikolaj Viktorovich
RU2761827C1
METHOD OF DETECTING TUMOR-FEEDING VESSELS IN EXPERIMENT 2008
  • Brusentsov Nikolaj Antonovich
  • Pirogov Jurij Andreevich
  • Brusentsova Tat'Jana Nikolaevna
  • Uchevatkin Andrej Alekseevich
  • Nikitin Petr Ivanovich
  • Ivanov Andrej Valentinovich
RU2382596C9
DIAGNOSTIC TECHNIQUE FOR GLIOBLASTOMA MULTIFORME BY MAGNETIC RESONANCE TOMOGRAPHY 2012
  • Abakumov Maksim Artemovich
  • Gubskij Il'Ja Leonidovich
  • Kabanov Aleksandr Viktorovich
  • Chekhonin Vladimir Pavlovich
RU2530762C2
FLUORESCENT GLIOMA CELL LINE AND METHOD FOR PRODUCTION THEREOF 2018
  • Shirokov Aleksandr Aleksandrovich
  • Fomin Aleksandr Sergeevich
  • Semyachkina-Glushkovskaya Oksana Valerevna
RU2699754C1
METHOD OF DIAGNOSTICS OF ONCOLOGIC DISEASES IN EXPERIMENT 2007
  • Brusentsov Nikolaj Antonovich
  • Brusentsova Tat'Jana Nikolaevna
  • Kuprijanov Dmitrij Alekseevich
  • Pirogov Jurij Andreevich
  • Dubina Andrej Ivanovich
  • Shumskikh Maksim Nikolaevich
RU2343828C2
METHOD FOR PREPARING A PREPARATION BASED ON MAGNETIC NANOPARTICLES (MNCH) OF IRON OXIDE FOR MRT-DIAGNOSIS OF NEOPLASMS 2017
  • Abakumov Maksim Artemovich
  • Mazhuga Aleksandr Georgievich
RU2659949C1
METHOD FOR INDICATING THE EFFECTIVENESS OF COMBINED ADAPTIVE STEREOTACTIC RADIOTHERAPY WITH BEVACIZUMAB IN MEN WITH MALIGNANT BRAIN GLIOMAS 2023
  • Kaplieva Irina Viktorovna
  • Vlasov Stanislav Grigorevich
  • Frantsiiants Elena Mikhailovna
  • Engibarian Marina Aleksandrovna
  • Sheiko Elena Aleksandrovna
  • Pogorelova Iuliia Aleksandrovna
  • Sakun Pavel Georgievich
  • Voshedskii Vitalii Igorevich
  • Trepitaki Lidiia Konstantinovna
  • Ishonina Oksana Georgievna
RU2801419C1
METHOD OF FERRIMAGNETIC-THERMOCHEMOTHERAPY OF MALIGNANT TUMOURS WITH COMBINATIONS OF MAGNETOCONTROLLABLE NANOMEDICINES WITH VISUALISATION OF ONCOGENESIS, DETEMINATION OF THERAPY PREFERABLE IN REAL TIME MODE AND MONITORING OF TREATMENT RESULTS IN EXPERIMENT 2014
  • Brusentsov Nikolaj Antonovich
  • Baryshnikov Anatolij Jur'Evich
  • Poljanskij Vitalij Aleksandrovich
  • Pirogov Jurij Andreevich
  • Dubina Andrej Ivanovich
  • Anisimov Nikolaj Viktorovich
  • Guljaev Mikhail Vladimirovich
  • Golubeva Irina Sergeevna
  • Tochilkin Anatolij Ivanovich
  • Brusentsova Tat'Jana Nikolaevna
  • Kuznetsov Vjacheslav Dmitrievich
  • Ksenevich Tat'Jana Ivanovna
  • Nikitin Sergej Ivanovich
  • Nikitina Irina L'Vovna
RU2563369C1
METHOD OF TREATING HIGH-GRADE GLIOMAS 2011
  • Chekhonin Vladimir Pavlovich
  • Jusubalieva Gaukhar Maratovna
  • Baklaushev Vladimir Pavlovich
  • Gurina Ol'Ga Ivanovna
RU2457862C1

RU 2 655 303 C2

Authors

Brusentsov Nikolaj Antonovich

Bocharova Olga Alekseevna

Polyanskij Vitalij Aleksandrovich

Pirogov Yurij Andreevich

Anisimov Nikolaj Viktorovich

Gulyaev Mikhail Vladimirovich

Nikitin Petr Ivanovich

Nikitin Maksim Petrovich

Dates

2018-05-24Published

2016-07-04Filed