FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to pharmaceutical industry, namely to a method for detection of Mycobacterium tuberculosis complex. Method for detection of Mycobacterium tuberculosis complex, comprises subjecting the Mycobacterium tuberculosis complex-specific protein to immunoassay, wherein said protein is secreted extracellularly by heat treatment of a biological sample containing Mycobacterium tuberculosis complex, at 45-50 °C for 15 to 60 minutes. Presented is a kit for detection of Mycobacterium tuberculosis complex and a method to secrete Mycobacterium tuberculosis specific proteins to extracellular.
EFFECT: described method allows to effectively detect the Mycobacterium tuberculosis complex.
15 cl, 2 dwg, 4 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANALYSIS OF MYCOBACTERIUM TUBERCULOSIS COMPLEX IMMUNODETECTION | 2008 |
|
RU2473095C2 |
| DIAGNOSTIC TECHNIQUE FOR MYCOBACTERIUM TUBERCULOSIS | 2015 |
|
RU2594063C1 |
| RECOMBINANT PLASMID DNA pTB323 CODING HYBRID POLYPEPTIDE CST-DELTAMPT64 WITH PROPERTIES OF SPECIES-SPECIFIC MYCOBACTERIAL ANTIGEN MPT64 (MPB64), RECOMBINANT ESCHERICHIA COLI BACTERIAL STRAIN - PRODUCER OF HYBRID POLYPEPTIDE CST-DELTAMPT64 AND RECOMBINANT POLYPEPTIDE CST-DELTAMPT64 | 2011 |
|
RU2458130C1 |
| BIOMARKERS FOR TUBERCULOSIS | 2014 |
|
RU2697549C2 |
| METHOD OF DETERMINING ANTIBODIES TO TUBERCULOSIS GERM | 2008 |
|
RU2395092C2 |
| HBHA-DETECTION OF TUBERCULOSIS AND MYCOBACTERIUM TUBERCULOSIS INFECTION | 2005 |
|
RU2426128C2 |
| METHOD OF IMMUNOCHROMATOGRAPHIC DETERMINATION OF SPECIFIC ANTIBODIES | 2013 |
|
RU2545909C2 |
| NITRITE-REDUCTASE AS POTENTIAL ANTI-TUBERCULAR TARGET AND METHOD TO DETECT SEVERITY OF TUBERCULOSIS | 2013 |
|
RU2671688C2 |
| METHOD OF CARRYING OUT IMMUNOCHROMATOGRAPHIC ANALYSIS FOR SERODIAGNOSTICS | 2012 |
|
RU2532352C2 |
| ANTIBODY AGAINST LIPOARABINOMANNAN AND IMMUNOASSAY OF INFECTIONS CAUSED BY ACID-FAST BACILLI, USING ANTIBODY | 2013 |
|
RU2588480C2 |
