FIELD: chemistry.
SUBSTANCE: invention relates to a process for the preparation of 5H-furo[3,2-c]isochromen-5-one of general formula I
,
where R = phenyl, substituted phenyl, ferrocenyl, 2-thienyl, which includes reacting ninhydrin with 1-alkynes in a 1,2-dichloroethane medium in the presence of 1 mol% scandium triflate for 1–3 hours.
EFFECT: simple and effective method for the preparation of novel isochromenone compounds, which may be of interest as intermediates for the synthesis of biologically active compounds.
1 cl, 1 tbl, 7 ex
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