METHOD FOR OBTAINING DERIVATIVES OF 1-(2-FURYL)-3,4-DIHYDROISOQUINOLINES Russian patent published in 2022 - IPC C07D405/04 C07D405/14 

Abstract RU 2786872 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to organic chemistry, or rather to a method for producing new heterocyclic compounds of a number of 3,4-dihydroisoquinolines, which may be of interest as analogues of biologically active compounds or intermediates for their synthesis. The method involves the interaction of 3,4-dihydroisoquinoline with furans in the presence of an equimolar amount of ethyl chloroformate in a 1,2-dichloroethane medium at room temperature for 1 hour, proceeding according to the scheme

EFFECT: simple and effective method for obtaining derivatives of 1-(2-furyl)-3,4-dihydroisoquinolines using commercially available compounds that make it possible to vary the substituent in the furan ring.

1 cl, 6 ex

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RU 2 786 872 C1

Authors

Konshin Valerij Viktorovich

Spesivaya Ekaterina Sergeevna

Konshina Dzhamilya Naibovna

Dates

2022-12-26Published

2021-12-28Filed