INACTIVATED MYCOBACTERIA FOR ORAL USE IN THE PREVENTION OF TUBERCULOSIS Russian patent published in 2018 - IPC A61K39/04 A61P31/06 

Abstract RU 2657753 C2

FIELD: medicine.

SUBSTANCE: method of preventing tuberculosis by oral intermittent administration of inactivated mycobacteria, with the interval between doses not exceeding 5 days, the number of doses of not less than 5. Technical result: tolerance response to infection by the tubercle bacillus is characterized by an increased proportion of regulatory T cells (Treg); providing a protective response due to control of induction of the disease when infected with mycobacteria and preventing recurrence of the treated active phase of tuberculosis.

EFFECT: inactivated bacteria can be used according to the aforementioned treatment regimen to control the progression of the infection from a latent state to active tuberculosis.

15 cl, 9 dwg, 7 ex

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RU 2 657 753 C2

Authors

Kardona Iglesias Pere-Khoan

Vilaplana Massakher Kristina

Marso Eskartin Elena

Dates

2018-06-15Published

2013-06-13Filed