FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine and is intended to predict the presence of chromosomal abnormalities in embryos of satisfactory and poor quality in the program of in vitro fertilization (IVF). Based on the analysis of the expression level of the mRNA of the PFKP gene in cumulus cells, the probability of the presence of aneuploidy in embryos of satisfactory and poor quality is determined by the formula. At p values above 0.5, the presence of chromosomal abnormalities in a given embryo group is predicted.
EFFECT: invention provides a model for predicting the presence of chromosomal abnormalities in embryos of satisfactory and poor quality based on the analysis of transcriptional activity in cumulus cells in patients in the infertility treatment in the IVF program.
1 cl, 1 tbl, 3 ex
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