FIELD: chemistry.
SUBSTANCE: invention relates to prodrugs of compounds comprising a nitric oxide donor and a reactive oxygen species (ROS) degradation catalyst, in particular, 1-pyrrolidinyloxy, 1-piperidinyloxy, and 1-azepanyloxy derivatives, and pharmaceutical compositions containing same. .
EFFECT: said compounds and pharmaceutical compositions are suitable for prevention, treatment or management of diseases, disorders or conditions associated with oxidative stress or endothelial dysfunction.
17 cl, 7 dwg, 11 tbl, 17 ex
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