NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME Russian patent published in 2018 - IPC C07D241/04 C07D241/12 A61K31/496 A61P29/00 

Abstract RU 2660897 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of formula I

, stereoisomers thereof or pharmaceutically acceptable salts thereof.

EFFECT: novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, used for the prevention or treatment of HDAC6-associated diseases, including cancer, inflammatory diseases, autoimmune diseases, neurological diseases and neurodegenerative disorders are obtained.

9 cl, 17 tbl, 253 ex

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RU 2 660 897 C2

Authors

Song Khieseung

Lee Changgon

Kvak Daliong

Lee Dzaeiung

Bae Sueal

Kim Yuntae

Bae Daekvon

Kha Nina

Bae Miseon

Kim Dzikhiun

Dates

2018-07-11Published

2015-03-12Filed