FIELD: medicine.
SUBSTANCE: invention relates to medical diagnostics and is intended to predict the risk of developing essential hypertension in women. Analysis of polymorphisms of MMP-1 and MMP-3 matrix metalloproteinase genes is carried out and a high risk of development of essential hypertension at women at revealing a combination of a genotype 1G/1G on a locus rs1799750 MMP-1 and a genotype 6A/6A on a locus rs3025058 MMP-3.
EFFECT: invention provides new criteria for assessing the risk of developing essential hypertension in women of Russian nationality, a native of the Central Chernozem region.
1 cl, 3 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING THE RISK OF DEVELOPING AN ISCHEMIC STROKE, TAKING INTO ACCOUNT GENETIC FACTORS | 2017 |
|
RU2653450C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING ESSENTIAL HYPERTENSION | 2017 |
|
RU2661604C1 |
| METHOD FOR PREDICTING THE RISK OF STROKE IN MEN BASED ON GENETIC TESTING | 2017 |
|
RU2664430C1 |
| METHOD FOR PREDICTION OF RISK OF ESSENTIAL HYPERTENSION DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2016 |
|
RU2624480C1 |
| METHOD FOR PREDICTION OF RISK OF PREECLAMPSIA DEVELOPMENT IN WOMEN DEPENDING ON HEREDITARY BURDEN | 2016 |
|
RU2646455C1 |
| METHOD FOR PREDICTING RISK OF DEVELOPMENT OF HYPERTENSIVE DISEASE FACTORED IN GENETIC AND ENVIRONMENTAL FACTORS | 2018 |
|
RU2678441C1 |
| METHOD FOR PREDICTION OF RISK OF PREECLAMPSIA DEVELOPMENT BASED ON MATRIX METAL PROTEINASE GENES COMBINATIONS | 2017 |
|
RU2646448C1 |
| METHOD FOR PREDICTION OF SEVERE PREECLAMPSIA DEVELOPMENT RISK CONSIDERING GENETIC DATA | 2017 |
|
RU2653765C1 |
| METHOD FOR PREDICTION OF MEN'S RISK OF ESSENTIAL HYPERTENSION ASSOCIATED WITH OBESITY | 2018 |
|
RU2693469C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING HYPERTENSIVE DISORDER BASED ON MOLECULAR AND GENETIC DATA | 2018 |
|
RU2679401C1 |
