FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology, oncology, and can be used to diagnose dysplasia and cervical cancer. Evaluate microcirculation in the altered region of the mucous membrane of the cervix by laser doppler flowmetry. Arithmetic mean of microcirculation (M), mean square deviation of the amplitude of blood flow oscillations from the arithmetic average value of the microcirculation index (σ), coefficient of variation (Kv), indicators of neurogenic (NT) and myogenic (MT) tone, shunting index (PN). With a value of M – 21.18 pf.ed, σ – 24.64, Kv – 116.36 %, at normal values of NT – 2.45 Hz, MT – 3.0 Hz and PN – 1.22 Hz diagnose mild cervical dysplasia (CIN I-II). With a value of M – 29.06 pf.ed, Kv – 94.15 %; NT – 1.84 Hz at normal values of MT – 2.79 Hz and PN – 1.51 Hz diagnose severe cervical dysplasia (CIN II-III). With a value of M – 28.06 pf.ed, σ – 24.42, Kv – 94.15 %, MT – 2.56 Hz and PN – 0.99 Hz diagnose cervical cancer in situ.
EFFECT: method provides non-invasive diagnostics of dysplasia and cervical cancer, improves its accuracy.
1 cl, 4 ex
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Authors
Dates
2018-07-26—Published
2016-06-27—Filed